Primary hyperaldosteronism Long test: 400 mg daily for 3-4 wk. Short test: 400 mg daily for 4 days. Pre-op: 100-400 mg daily. Edema in adult w/ CHF, hepatic cirrhosis or nephrotic syndrome Initially 100 mg in single or divided doses or 25-200 mg daily. Sole agent for diuresis: Continued for at least 5 days at the initial dosage level, may be adjusted to the optimal therapeutic or maintenance level administered in either single or divided daily doses. Essential HTN in adult Initially 50-100 mg in single or divided doses. Hypokalemia 25-100 mg daily.
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